ABSTRACTrnTHE EFFECT OF CUPPING THERAPY ON CHOLESTEROL REDUCTION IN PATIENTS WITH HYPERCHOLESTEROLEMIA rnrnAgustina ratna sari, Saifudin Zukhri, Fitriana Noor KhayatirnrnrnBackground: Hypercholesterolemia is a risk factor cause of death at a young ages. Hypercholesterolemia may increase the risk of atherosclerosis, coronary heart disease, stroke, diabetes mellitus, thyroid disorders, liver and kidney disease. Many patients with hiperkoleterolemia using cupping therapy. Cupping therapy can make the alternative solution in hypercholesterolemia patients to lower blood cholesterol levels.rnPurpose: To determine the effect of cupping therapy to decrease cholesterol levels in hypercholesterolemic patients in clinics and pharmacies migoenani healthy.rnMethods: This study used a pre-experimental research design with the design of one group pre test post test design. The population in this study were all hypercholesterolemic patients in clinics and pharmacies migoenani klaten healthy. Large sample of 18 respondents was obtained by using purposive sampling technique. This study uses data analysis paired t-test.rnResults: The results of the analysis using a paired t-test values obtained pvalue = 0.00 (pvalue